Androgen regulates follicle-stimulating hormone beta gene expression in an activin-dependent manner in immortalized gonadotropes.

@article{Spady2004AndrogenRF,
  title={Androgen regulates follicle-stimulating hormone beta gene expression in an activin-dependent manner in immortalized gonadotropes.},
  author={Thomas J. Spady and Rana F. Shayya and Varykina G. Thackray and Lisa Ehrensberger and Janice S Bailey and Pamela L Mellon},
  journal={Molecular endocrinology},
  year={2004},
  volume={18 4},
  pages={925-40}
}
Little is known about the molecular mechanisms of androgen regulation of the FSHbeta gene; however, studies suggest that it consists of a complex feedback loop that involves multiple mechanisms acting at both the level of the hypothalamus and the pituitary. In the present study, we address androgen regulation of the FSHbeta gene in immortalized gonadotrope… CONTINUE READING