Androgen regulates development of the sexually dimorphic gastrin-releasing peptide neuron system in the lumbar spinal cord: evidence from a mouse line lacking androgen receptor in the nervous system.

@article{Sakamoto2014AndrogenRD,
  title={Androgen regulates development of the sexually dimorphic gastrin-releasing peptide neuron system in the lumbar spinal cord: evidence from a mouse line lacking androgen receptor in the nervous system.},
  author={Hirotaka Sakamoto and Kazuhiro Saito and Clarisse Marie-Luce and Kalina Raskin and Takumi Oti and Keita Satoh and Kei Tamura and Tatsuya Sakamoto and Sakina Mhaouty-Kodja},
  journal={Neuroscience letters},
  year={2014},
  volume={558},
  pages={109-14}
}
Androgens including testosterone, organize the nervous system as well as masculine external and internal genitalia during the perinatal period. Androgen organization involves promotion of masculine body features, usually by acting through androgen receptors (ARs). We have recently demonstrated that the gastrin-releasing peptide (GRP) system in the lumbar spinal cord also mediates spinal centers promoting penile reflexes during male sexual behavior in rats. Testosterone may induce sexual… CONTINUE READING
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