Androgen regulated expression of a spermine binding protein gene in mouse ventral prostate.

@article{Mills1987AndrogenRE,
  title={Androgen regulated expression of a spermine binding protein gene in mouse ventral prostate.},
  author={J. S. Mills and M. Needham and Malcolm G. Parker},
  journal={Nucleic acids research},
  year={1987},
  volume={15 19},
  pages={7709-24}
}
A full length cDNA (MP25) encoding the major mouse prostatic secretory glycoprotein (p25), whose expression is androgen dependent, has been cloned and characterised. Steady-state levels of mRNA are decreased approximately 100-fold after 3 days castration but are restored progressively over 4 days with testosterone treatment. The secreted glycoprotein appears to be a spermine binding protein since the nucleotide and predicted amino acid sequence of MP25 shares extensive homology with a spermine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…