Androgen receptors.

  title={Androgen receptors.},
  author={Gary David Berkovitz and Terry R. Brown and Claude J. Migeon},
  journal={Clinics in endocrinology and metabolism},
  volume={12 1},
Testosterone and its active metabolite dihydrotestosterone exert their influence on target cells through a specific intracellular protein receptor. Structural abnormalities of this receptor lead to a diminished androgen action within the cell and result in the syndrome of androgen insensitivity. Androgen insensitivity is classified on the basis of whether the insensitivity is complete or partial and whether the androgen receptor is normally present (AR(+)), absent (AR(-)) or diminished (AR… CONTINUE READING