Androgen receptors may act in a paracrine manner to regulate oesophageal adenocarcinoma growth.

@article{Awan2007AndrogenRM,
  title={Androgen receptors may act in a paracrine manner to regulate oesophageal adenocarcinoma growth.},
  author={Altaf K. Awan and Syed Yousef Iftikhar and Teresa M Morris and Pamela A G Clarke and Anna Grabowska and Naseem G Waraich and Susan A. Watson},
  journal={European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology},
  year={2007},
  volume={33 5},
  pages={561-8}
}
BACKGROUND The role of androgen receptors (ARs) in tumorigenesis, including transcription of fibroblast growth factors (FGFs), is established in prostate cancer. This study examined the role of ARs and FGFs in oesophageal adenocarcinoma (EAC), where tumour incidence in males is higher. METHODS AR gene expression was analysed using quantitative RT-PCR; AR, fibroblast growth factor receptor-1 (FGFR-1) and fibroblast growth factor-8 isoform b (FGF-8b) protein by immunohistochemistry; and serum… CONTINUE READING

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