Androgen receptor roles in hepatocellular carcinoma, fatty liver, cirrhosis and hepatitis.

@article{Ma2014AndrogenRR,
  title={Androgen receptor roles in hepatocellular carcinoma, fatty liver, cirrhosis and hepatitis.},
  author={Wen-Lung Ma and Hsueh-Chou Lai and Shuyuan Yeh and Xiujun Cai and Chawnshang Chang},
  journal={Endocrine-related cancer},
  year={2014},
  volume={21 3},
  pages={
          R165-82
        }
}
Androgen/androgen receptor (AR) signaling plays important roles in normal liver function and in progression of liver diseases. In studies of noncancerous liver diseases, AR knockout mouse models of liver disease have revealed that androgen/AR signaling suppresses the development of steatosis, virus-related hepatitis, and cirrhosis. In addition, studies have shown that targeting AR in bone marrow-derived mesenchymal stem cells (BM-MSCs) improves their self-renewal and migration potentials… CONTINUE READING

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