Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones.

Abstract

Nuclear transport, phosphorylation, ligand binding, and degradation rate of the recombinant androgen receptor (AR) were analyzed in transfected COS cells in the presence of various steroids and antiandrogens. Transcriptional activation was assessed in CV1 cells by cotransfection with an androgen-responsive chloramphenicol acetyltransferase (CAT) reporter… (More)

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Cite this paper

@article{Kemppainen1992AndrogenRP, title={Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones.}, author={John Kemppainen and Maria V. Lane and Mehmet Sar and Elizabeth M. Wilson}, journal={The Journal of biological chemistry}, year={1992}, volume={267 2}, pages={968-74} }