Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells.

@article{Baron2004AndrogenRM,
  title={Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells.},
  author={Silv{\`e}re Baron and Mich{\`e}le Manin and Claude Beaudoin and Laurent L{\'e}otoing and Yves Communal and Georges M. Veyssiere and Laurent Ach Benoit Morel},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 15},
  pages={14579-86}
}
Androgens are known to modulate many cellular processes such as cell growth and survival by binding to the androgen receptor (AR) and activating the transcription of target genes. Recent data suggested that AR can also mediate non-transcriptional actions outside the nucleus in addition to its ligand-inducible transcription factor function. Here, we describe a transcription-independent activation of the phosphatidylinositol 3-OH kinase (PI3-K) signaling pathway by androgens. Using non… CONTINUE READING
58 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

Similar Papers

Loading similar papers…