Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma.

Abstract

BACKGROUND & AIMS Androgen effects on hepatocellular carcinoma (HCC) remain controversial and androgen ablation therapy to treat HCC also leads to inconsistent results. Here we examine androgen receptor (AR) roles in hepatocarcinogenesis using mice lacking AR in hepatocytes. METHODS By using the Cre-Lox conditional knockout mice model injected with… (More)
DOI: 10.1053/j.gastro.2008.05.046

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