Androgen receptor interacts with a novel MYST protein, HBO1.

  title={Androgen receptor interacts with a novel MYST protein, HBO1.},
  author={Manju Sharma and Mark A. Zarnegar and X Li and Bing Lim and Zijie Sun},
  journal={The Journal of biological chemistry},
  volume={275 45},
The androgen receptor (AR), a member of the nuclear receptor superfamily, plays a central role in male sexual differentiation and prostate cell proliferation. Results of treating prostate cancer by androgen ablation indicate that signals mediated through AR are critical for the growth of these tumors. Like other nuclear receptors, AR exerts its transcriptional function by binding to cis-elements upstream of promoters and interacting with other transcriptional factors (e.g. activators… CONTINUE READING


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