Androgen receptor gene expression in rat granulosa cells: the role of follicle-stimulating hormone and steroid hormones.

@article{Tetsuka1996AndrogenRG,
  title={Androgen receptor gene expression in rat granulosa cells: the role of follicle-stimulating hormone and steroid hormones.},
  author={Masafumi Tetsuka and Stephen G. Hillier},
  journal={Endocrinology},
  year={1996},
  volume={137 10},
  pages={
          4392-7
        }
}
In rat ovary, androgen receptor (AR) is predominantly expressed in granulosa cells and is developmentally regulated. However, the exact mechanism that is responsible for the regulation of AR in granulosa cells has not been elucidated. The aim of this study was to examine 1) the levels of AR messenger RNA (mRNA) expression in granulosa cells from follicles of different size and 2) the effects of FSH, 8-bromo-cAMP, androgen, and estrogen on AR mRNA levels in granulosa cells in vitro. The… CONTINUE READING
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