Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression.

Abstract

BACKGROUND Recently we reported that silencing the androgen receptor (AR) gene reduced Bcl-xL expression that was associated with a profound apoptotic cell death in prostate cancer cells. In this study we further investigated AR-regulated Bcl-xL expression. METHODS Prostate cancer cell line LNCaP and its sublines, LNCaP/PURO and LNCaP/Bclxl, were used for… (More)
DOI: 10.1002/pros.20723

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