Androgen receptor complexes probe DNA for recognition sequences by short random interactions.

  title={Androgen receptor complexes probe DNA for recognition sequences by short random interactions.},
  author={Martin E van Royen and Wiggert A van Cappellen and Bart Geverts and Thomas Schmidt and Adriaan B. Houtsmuller and Marcel J M Schaaf},
  journal={Journal of cell science},
  volume={127 Pt 7},
Owing to the tremendous progress in microscopic imaging of fluorescently labeled proteins in living cells, the insight into the highly dynamic behavior of transcription factors has rapidly increased over the past decade. However, a consistent quantitative scheme of their action is still lacking. Using the androgen receptor (AR) as a model system, we combined three different fluorescence microscopy assays: single-molecule microscopy, photobleaching and correlation spectroscopy, to provide a… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 64 references

Structural basis of androgen receptor binding to selective androgen response elements.

Proceedings of the National Academy of Sciences of the United States of America • 2004
View 4 Excerpts
Highly Influenced

Evidence for a common mode of transcription factor interaction with chromatin as revealed by improved quantitative fluorescence recovery after photobleaching

F. Mueller, P. Wach, J. G. McNally
Biophys. J • 2008
View 6 Excerpts
Highly Influenced

The road much traveled: trafficking in the cell nucleus.

Current opinion in cell biology • 2006
View 4 Excerpts
Highly Influenced

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