Androgen receptor complexes probe DNA for recognition sequences by short random interactions.

@article{Royen2014AndrogenRC,
  title={Androgen receptor complexes probe DNA for recognition sequences by short random interactions.},
  author={Martin E van Royen and Wiggert A van Cappellen and Bart Geverts and Thomas Schmidt and Adriaan B. Houtsmuller and Marcel J M Schaaf},
  journal={Journal of cell science},
  year={2014},
  volume={127 Pt 7},
  pages={1406-16}
}
Owing to the tremendous progress in microscopic imaging of fluorescently labeled proteins in living cells, the insight into the highly dynamic behavior of transcription factors has rapidly increased over the past decade. However, a consistent quantitative scheme of their action is still lacking. Using the androgen receptor (AR) as a model system, we combined three different fluorescence microscopy assays: single-molecule microscopy, photobleaching and correlation spectroscopy, to provide a… CONTINUE READING
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