Androgen receptor and molecular mechanisms of male-specific gene expression.

@article{Robins2005AndrogenRA,
  title={Androgen receptor and molecular mechanisms of male-specific gene expression.},
  author={Diane M. Robins},
  journal={Novartis Foundation symposium},
  year={2005},
  volume={268},
  pages={42-52; discussion 53-6, 96-9}
}
Androgen's central role in male differentiation, fertility and aggression is evident from human pathologies and animal behaviour studies. Androgens directly regulate gene expression via the androgen receptor (AR), a member of the nuclear receptor superfamily. Nuclear receptors share a modular structure, with specialized domains for DNA binding, ligand… CONTINUE READING