Androgen-insensitive rats are defeminised by their testes

@article{Olsen1979AndrogeninsensitiveRA,
  title={Androgen-insensitive rats are defeminised by their testes},
  author={Kathie L. Olsen},
  journal={Nature},
  year={1979},
  volume={279},
  pages={238-239}
}
SOME chromosomal XY male humans1, mice2,3 and rats4 are born with a vagina, labia and clitoris instead of scrotum and penis. The expression of the female phenotype in these individuals is thought to be due to an insensitivity to androgenic hormones which are secreted by the testes. This phenomenon has been termed the androgen-insensitivity syndrone or testicular feminisation. Typically, androgen-insensitive humans are identified and adopt a female gender identity5. Androgen-insensitive rats, on… CONTINUE READING
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