Androgen-estrogen synergy in rat levator ani muscle: glucose-6-phosphate dehydrogenase

@article{Max1984AndrogenestrogenSI,
  title={Androgen-estrogen synergy in rat levator ani muscle: glucose-6-phosphate dehydrogenase},
  author={Stephen R. Max},
  journal={Molecular and Cellular Endocrinology},
  year={1984},
  volume={38},
  pages={103-107}
}
  • S. R. Max
  • Published 31 December 1984
  • Biology, Medicine
  • Molecular and Cellular Endocrinology
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TLDR
A direct effect of estrogen on striated muscle is demonstrated and appears to be mediated by conversion of testosterone to estradiol.
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It is suggested that estrogen treatment is required for the induction and maintenance of the androgen cytoplasmic receptor and that the ability of androgens to modulate magnum growth and ovalbumin mRNA levels correlates with the concentration of this receptor.
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It is reported that the effect of denervation on glucose 6‐phosphate dehydrogenase activity is modified by variations in endogenous estradiol during the estrous cycle.
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