Androgen and menopause

  title={Androgen and menopause},
  author={Woraluk Somboonporn},
  journal={Current Opinion in Obstetrics and Gynecology},
  • W. Somboonporn
  • Published 1 August 2006
  • Medicine, Biology
  • Current Opinion in Obstetrics and Gynecology
Purpose of review Androgen therapy is being increasingly used in the management of postmenopausal women. The most common indication is to improve sexual function. The aim of this review is to evaluate current knowledge pertaining to testosterone and sexual function in postmenopausal women. Recent findings The change of testosterone levels during the menopause transition remains controversial. A correlation of endogenous testosterone levels and sexual function is still inconclusive. A Cochrane… 

Androgens And Sexual Function During Menopause.

A collection of 44 articles related to androgens and sexual function, which were published from 2003 to 2014, were studied and demonstrated a correlation between androgens, including testosterone, and sexual satisfaction and function, but some other studies do not report any correlation.

Effectiveness of a low dose testosterone undecanoate to improve sexual function in postmenopausal women

The twice weekly addition of testosterone undecanoate to daily oral estrogen was associated with a significant improvement in sexual function among postmenopausal women than the use of the estrogen alone.

Sex steroids in Sjögren's syndrome.



Androgen replacement in women: a commentary.

  • S. Davis
  • Medicine, Biology
    The Journal of clinical endocrinology and metabolism
  • 1999
The rationale for the use of testosterone in women is reviewed, awareness of some of the therapeutic options available in various countries are created, and discussion of this important aspect of women's health are stimulated.

Androgen enhances sexual motivation in females: a prospective, crossover study of sex steroid administration in the surgical menopause.

It was clear that exogenous androgen enhanced the intensity of sexual desire and arousal and the frequency of sexual fantasies in hysterectomized and oophorectomization women, but there was no evidence that testosterone affected physiologic response or interpersonal aspects of sexual behavior.

Testosterone patch increases sexual activity and desire in surgically menopausal women with hypoactive sexual desire disorder.

In the Intimate SM 1 study, the testosterone patch improved sexual function and decreased distress in surgically menopausal women with HSDD and was well tolerated in this trial.

Effects of aromatase inhibition on sexual function and well-being in postmenopausal women treated with testosterone: a randomized, placebo-controlled trial

Increases in total and free T in the physiologic range in postmenopausal women were associated with improved sexual satisfaction, well-being, and mood, and aromatase inhibition did not influence any of these outcomes.

Transdermal testosterone therapy improves well-being, mood, and sexual function in premenopausal women

Testosterone therapy improves well-being, mood, and sexual function in premenopausal women with low libido and low testosterone.

Differential effects of oral estrogen versus oral estrogen-androgen replacement therapy on body composition in postmenopausal women.

In conclusion, E/A replacement therapy can improve body composition, lower-body muscle strength, quality of life, and sexual functioning in postmenopausal women.

Hormonal treatments of sexual unresponsiveness in postmenopausal women: a comparative study

Although it is not possible to identify the reasons for change, the results indicate no advantages of supplementary testosterone administration over oestradiol alone for sexually unresponsive postmenopausal women.