Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells

@article{Poulin2005AndrogenAG,
  title={Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells},
  author={R. Poulin and D. Baker and D. Poirier and F. Labrie},
  journal={Breast Cancer Research and Treatment},
  year={2005},
  volume={13},
  pages={161-172}
}
Medroxyprogesterone acetate (MPA) is a synthetic progestin, currently used in the adjuvant treatment of advanced breast cancer, which induces remission rates (30–40%) comparable to those obtained with other types of endocrine therapies. Since, in addition to its progestin-like action, MPA exhibits androgen- and glucocorticoid-like activities in other tissues, the present study was designed to assess the relative contribution of the different steroid receptor systems in the direct action of MPA… Expand
Role of the Androgen Receptor in Human Breast Cancer
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References

SHOWING 1-10 OF 71 REFERENCES
An antiestrogenic action of androgens in human breast cancer cells.
  • J. MacIndoe, L. Etre
  • Biology, Medicine
  • The Journal of clinical endocrinology and metabolism
  • 1981
Medroxyprogesterone acetate: receptor binding and correlated effects on steroidogenesis in rat granulosa cells.
The role of progestins in the treatment of breast cancer.
Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer.
...
1
2
3
4
5
...