Androgen and estrogen receptors in embryonic and neonatal rat brain.


We provide biochemical evidence that specific androgen- and estrogen-binding macromolecules are present in rat hypothalamus-preoptic area throughout the "critical period' of brain sexual differentiation. Macromolecules with the properties of putative androgen and estrogen receptors are present in cytosolic extracts of embryonic neonatal, prepubertal rat… (More)


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