Androgen- and estrogen-binding macromolecules in developing mouse brain: biochemical and genetic evidence.

  • Trevor Fox
  • Published 1975 in
    Proceedings of the National Academy of Sciences…

Abstract

Androgen- and estrogen-binding macromolecules from the hypothalamus plus preoptic area of 3- to 4-week-old mice have been detected and partially characterized. These components bind the respective hormones with high affinity (saturating at 4-8 nM) and sediment with rates typical of presumed steroid receptors (4.0-4.5 S in 0.15 M NaCl, 5.0-7.5 S without salt… (More)

Topics

  • Presentations referencing similar topics