Androgen activation of the sterol regulatory element-binding protein pathway: Current insights.

@article{Heemers2006AndrogenAO,
  title={Androgen activation of the sterol regulatory element-binding protein pathway: Current insights.},
  author={Hannelore V. Heemers and Guido Verhoeven and Johannes V Swinnen},
  journal={Molecular endocrinology},
  year={2006},
  volume={20 10},
  pages={2265-77}
}
The cellular effects of androgens are mediated by a cognate receptor, the androgen receptor. Typically, the androgen receptor is viewed to exert its activity by binding to androgen response elements located in or near the promoter region of target genes, thereby directly affecting the expression of these genes. However, increasing evidence indicates that androgens may also indirectly influence the expression of genes that do not contain androgen response elements by modulating the activity of… CONTINUE READING
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