Androgen actions and the ovary.

  title={Androgen actions and the ovary.},
  author={Kirsty A. Walters and Charles M. Allan and David J Handelsman},
  journal={Biology of reproduction},
  volume={78 3},
Although androgens and the androgen receptor (AR) have defining roles in male reproductive development and function, previously no role in female reproductive physiology beyond testosterone (T) as the precursor in estradiol (E(2)) biosynthesis was firmly established. Understanding the role and specific mechanisms of androgen action via the AR in the ovary has been limited by confusion on how to interpret results from pharmacological studies, because many androgens can be metabolized in vivo and… CONTINUE READING


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