Androgen action via testicular peritubular myoid cells is essential for male fertility

@article{Welsh2009AndrogenAV,
  title={Androgen action via testicular peritubular myoid cells is essential for male fertility},
  author={Michelle Welsh and Philippa T K Saunders and Nina Atanassova and Richard M. Sharpe and Lee B. Smith},
  journal={The FASEB Journal},
  year={2009},
  volume={23},
  pages={4218 - 4230}
}
Androgens are essential for normal spermatogenesis and male fertility, but how androgens exert this effect remains uncertain. Androgen receptors (ARs) are expressed in several testicular cell types, but continuing uncertainty exists over which cell type mediates androgen control of spermatogenesis. Androgen signaling via Sertoli cells (SCs) is essential for complete spermatogenesis, but the role for androgen signaling via peritubular myoid (PTM) cells is contentious. To address this controversy… CONTINUE READING

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