Androgen action on human skin – from basic research to clinical significance

  title={Androgen action on human skin – from basic research to clinical significance},
  author={C. Zouboulis and K. Degitz},
  journal={Experimental Dermatology},
  • C. Zouboulis, K. Degitz
  • Published 2004
  • Medicine, Biology
  • Experimental Dermatology
  • Abstract:  Androgens affect several functions of the human skin, such as sebaceous gland growth and differentiation, hair growth, epidermal barrier homeostasis and wound healing. Their effects are mediated by binding to nuclear androgen receptors. Androgen activation and deactivation are mainly intracellular events. They differ from cell type to cell type and between cells at different locations. The major circulating androgens, dehydroepiandrosterone sulfate and androstenedione, are… CONTINUE READING
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