Androgen Replacement in Aging Men

@article{Francis2001AndrogenRI,
  title={Androgen Replacement in Aging Men},
  author={Roger M. Francis},
  journal={Calcified Tissue International},
  year={2001},
  volume={69},
  pages={235-238}
}
  • R. Francis
  • Published 27 September 2001
  • Medicine, Biology
  • Calcified Tissue International
Serum testosterone and estradiol decline with advancing age in men, but the contribution of these changes to age-related bone loss remains unclear. Most studies show a closer relationship between bone density and serum estradiol than with serum testosterone. Nevertheless, hypogonadism is widely considered to be an important cause of male osteoporosis, occurring in up to 20% of men with vertebral fractures and 50% with hip fractures. Bone loss in hypogonadal men has been attributed to androgen… 
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