Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne

@article{Sawaya1998AndrogenRP,
  title={Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne},
  author={M. Sawaya and A. Shalita},
  journal={Journal of Cutaneous Medicine and Surgery},
  year={1998},
  volume={3},
  pages={15 - 9}
}
Background: The androgen receptor (AR) is a structurally conserved member of the nuclear receptor superfamily. The amino-terminal domain is required for transcriptional activation and contains a region of polyglutamine encoded by CAG trinucleotide repeats. In humans, the number of CAG repeats is polymorphic. Expansion of CAG repeats in the AR has clinical implications for human disease. Objective: Androgens influence androgenetic alopecia (AGA), hirsutism, and acne; the polymorphisms in CAG… Expand
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TLDR
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TLDR
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