Androgen Receptor Drives Cellular Senescence

Abstract

The accepted androgen receptor (AR) role is to promote proliferation and survival of prostate epithelium and thus prostate cancer progression. While growth-inhibitory, tumor-suppressive AR effects have also been documented, the underlying mechanisms are poorly understood. Here, we for the first time link AR anti-cancer action with cell senescence in vitro… (More)
DOI: 10.1371/journal.pone.0031052

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Cite this paper

@inproceedings{Mirochnik2012AndrogenRD, title={Androgen Receptor Drives Cellular Senescence}, author={Yelena Mirochnik and Dorina Veliceasa and Latanya Veronica Williams and Kelly E. Maxwell and Alexander Y Yemelyanov and Irina V. Budunova and Olga V. Volpert}, booktitle={PloS one}, year={2012} }