Androgen-Induced Relaxation of Uterine Myocytes Is Mediated by Blockade of Both Ca(2+) Flux and MLC Phosphorylation.

Abstract

CONTEXT Uterine quiescence must be maintained until pregnancy reaches term. Premature activation of myometrial contractility leads to preterm labor and delivery. OBJECTIVE To scrutinize the potential of androgens to relax the myometrium and the mechanism of their action. SAMPLES A pregnancy-derived myometrial smooth muscle cell line (PHM1-41) and… (More)
DOI: 10.1210/jc.2015-2851

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