Andrimid, a new peptide antibiotic produced by an intracellular bacterial symbiont isolated from a brown planthopper

  title={Andrimid, a new peptide antibiotic produced by an intracellular bacterial symbiont isolated from a brown planthopper},
  author={A. Fredenhagen and S. Tamura and P. T. Kenny and H. Komura and Y. Naya and K. Nakanishi and K. Nishiyama and M. Sugiura and H. Kita},
  journal={Journal of the American Chemical Society},
Biosynthesis of the acetyl‐CoA carboxylase‐inhibiting antibiotic, andrimid in Serratia is regulated by Hfq and the LysR‐type transcriptional regulator, AdmX
It is shown that Serratia plymuthica A153 produces a second broad spectrum antibiotic, andrimid, an antibiotic with potential clinical and agricultural utility and the complexity of andrimids biosynthesis is highlighted. Expand
Andrimid production at low temperature by a psychrotolerant Serratia proteamaculans strain
The work demonstrated the significance of bioprospection from cold environments through the screening of microorganisms with ability to produce cold-active biomolecules of biotechnological interest and revealed S. proteamaculans 136 as a novel microbial source for andrimid production at low temperatures, showing biotehnological potential to be applied in cryopreservation, food or cosmetic industries against pathogenic bacteria. Expand
Targeted antibiotic discovery through biosynthesis-associated resistance determinants: target directed genome mining
A strategy to mine microbial genomes for these genes and their associated biosynthetic gene clusters to discover novel antibiotics using target directed genome mining is proposed. Expand
Antagonistic Interactions among Marine Bacteria Impede the Proliferation of Vibrio cholerae
It was found that some marine bacteria are capable of inhibiting the growth of V. cholerae on surfaces and that bacterial isolates derived from pelagic particles show a greater frequency of V-cholerae inhibition than free-living bacteria. Expand
Biologically active peptides from marine proteobacteria: Discussion article
Identifying the alterations occurred in the bacteriology of the dermic layer of the abdominal wall in patients who underwent a colostomy, through the qualitative and quantitative determination of theExpand
Comparative genomic of biosynthetic gene cluster of andrimid antibiotic from Serratia plymuthica UBCF_13
Serratia plymuthica UBCF_13 was a promising bacterium to control plant pathogenic fungal. Availability of this bacterium genome and genome mining approaches has assisted to identify gene-encodedExpand
Developmental stage-associated microbiota profile of the peach fruit fly, Bactrocera zonata (Diptera: Tephritidae) and their functional prediction using 16S rRNA gene metabarcoding sequencing
The microbiota that was shared by all the developmental stages of B. zonata in the present study could be targeted and the foundation for research on microbiota-based management of fruit flies is built. Expand
Antagonism of Quorum Sensing Phenotypes by Analogs of the Marine Bacterial Secondary Metabolite 3-Methyl-N-(2′-Phenylethyl)-Butyramide
It is reported that N-phenethyl hexanamide, a structurally-related compound produced by the marine bacterium Vibrio neptunius, similarly demonstrates QS inhibitory properties and supports the opportunity to further develop substituted phenethylamides as QS inhibitors. Expand
Genome annotation and antimicrobial properties of Bacillus toyonensis VU‐DES13, isolated from the Folsomia candida gut
A unique Bacillus strain was isolated from the gut of F. candida, for which evidence of inhibitory activity against an array of pathogens is provided, pointing to the potential of B. toyonensis VU‐DES13 to provide a new source of antimicrobial compounds. Expand