Ancrod in acute ischemic stroke: results of 500 subjects beginning treatment within 6 hours of stroke onset in the ancrod stroke program.

@article{Levy2009AncrodIA,
  title={Ancrod in acute ischemic stroke: results of 500 subjects beginning treatment within 6 hours of stroke onset in the ancrod stroke program.},
  author={David E. Levy and Gregory John del Zoppo and Bart M. Demaerschalk and A M Demchuk and Hans-Christoph Diener and G. Howard and Markku Kaste and Arthur Martin Pancioli and E. Bernd Ringelstein and Carmen Spatareanu and Warren W Wasiewski},
  journal={Stroke},
  year={2009},
  volume={40 12},
  pages={3796-803}
}
BACKGROUND AND PURPOSE Previous studies of multiple-day dosing with the defibrinogenating agent, ancrod, in acute ischemic stroke yielded conflicting results but suggested that a brief dosing regimen might improve efficacy and safety. The Ancrod Stroke Program was designed to test this concept in subjects beginning ancrod or placebo within 6 hours of the onset of acute ischemic stroke. METHODS Five hundred subjects with acute ischemic stroke who could begin receiving study material within 6… CONTINUE READING
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