Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics.

@article{Perry2003AncillaryFA,
  title={Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics.},
  author={Arie Perry and Christine e. Fuller and Ruma Banerjee and Daniel J. Brat and Bernd Walter Scheithauer},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2003},
  volume={8},
  pages={a1-9}
}
Deletions of chromosomes 1p and 19q are associated with chemosensitivity and enhanced survival in oligodendrogliomas. Therefore, we have utilized FISH analysis as an ancillary tool for diffuse gliomas with suspected oligodendroglial features. To date, 246 gliomas have been analyzed in 131 male and 93 female patients, including 109 oligodendrogliomas (O), 109 mixed oligoastrocytomas/equivocal gliomas (MOA), and 28 astrocytomas (A). To address specificity, we also analyzed 41 oligodendroglioma… CONTINUE READING
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