Ancient origin of the Hox gene cluster

@article{Ferrier2001AncientOO,
  title={Ancient origin of the Hox gene cluster},
  author={David E. K. Ferrier and Peter W H Holland},
  journal={Nature Reviews Genetics},
  year={2001},
  volume={2},
  pages={33-38}
}
The Hox gene cluster has a crucial function in body patterning during animal development. How and when this gene cluster originated is being clarified by recent data from Cnidaria, a basal animal phylum. The characterization of Hox-like genes from Hydra, sea anemones and jellyfish has revealed that a Hox gene cluster is extremely ancient, having originated even before the divergence of these basal animals. 
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