Ancient disease resistance made us vulnerable to HIV

  title={Ancient disease resistance made us vulnerable to HIV},
  author={Michael Hopkin},
  • M. Hopkin
  • Published 21 June 2007
  • Medicine
  • Nature
Early immune resistance may have helped to set stage for modern pandemic. 


Restriction of an Extinct Retrovirus by the Human TRIM5α Antiviral Protein
It is suggested that selective changes that have occurred in the human lineage during the acquisition of resistance to this virus, and perhaps similar viruses, may have left the authors' species more susceptible to infection by human immunodeficiency virus type 1 (HIV-1).