Ancient Origin of Four-Domain Voltage-gated Na+ Channels Predates the Divergence of Animals and Fungi

@article{Cai2012AncientOO,
  title={Ancient Origin of Four-Domain Voltage-gated Na+ Channels Predates the Divergence of Animals and Fungi},
  author={Xinjiang Cai},
  journal={The Journal of Membrane Biology},
  year={2012},
  volume={245},
  pages={117-123}
}
The four-domain voltage-gated Na+ channels are believed to have arisen in multicellular animals, possibly during the evolution of the nervous system. Recent genomic studies reveal that many ion channels, including Na+ channels and Ca2+ channels previously thought to be restricted to animals, can be traced back to one of the unicellular ancestors of animals… CONTINUE READING