Ancient DNA from the First European Farmers in 7500-Year-Old Neolithic Sites

@article{Haak2005AncientDF,
  title={Ancient DNA from the First European Farmers in 7500-Year-Old Neolithic Sites},
  author={W. Haak and P. Forster and B. Bramanti and S. Matsumura and Guido Brandt and Marc Taenzer and R. Villems and C. Renfrew and D. Gronenborn and K. Alt and J. Burger},
  journal={Science},
  year={2005},
  volume={310},
  pages={1016 - 1018}
}
The ancestry of modern Europeans is a subject of debate among geneticists, archaeologists, and anthropologists. A crucial question is the extent to which Europeans are descended from the first European farmers in the Neolithic Age 7500 years ago or from Paleolithic hunter-gatherers who were present in Europe since 40,000 years ago. Here we present an analysis of ancient DNA from early European farmers. We successfully extracted and sequenced intact stretches of maternally inherited… Expand
DNAs from the European Neolithic
TLDR
A stretch of ancient mitochondrial DNA is typed in the largest sample so far from European prehistoric farming communities, successfully amplified and typed 24 mitochondrial sequences from skeletons excavated in 16 Neolithic sites in Germany, Hungary and Austria. Expand
Ancient DNA insights from the Middle Neolithic in Germany
Genetic studies of Neolithic groups in central Europe have provided insights into the demographic processes that have occurred during the initial transition to agriculture as well as in laterExpand
Complete Mitochondrial Genomes Reveal Neolithic Expansion into Europe
TLDR
The observed changes over time suggest that the spread of agriculture in Europe involved the expansion of farming populations into Europe followed by the eventual assimilation of resident hunter-gatherers. Expand
ANCIENT MITOCHONDRIAL DNA POLYMORPHISMS FROM HUMAN NEOLITHIC SITES IN THE CARPATHIAN BASIN
TLDR
Direct DNA sequence analysis of PCR products of interest showed that HVR of the mitochondrial DNA contain point mutations just specifically bound to the 8, 000-year-old aDNA, and the distinctive mutation patterns of nt16257 and nt 16261 were repeatedly found, which is characteristic of the N9a mitochondrial haplogroup. Expand
Ancient DNA Reveals Key Stages in the Formation of Central European Mitochondrial Genetic Diversity
TLDR
This transect through time reveals four key population events associated with well-known archaeological cultures, which involved genetic influx into Central Europe from various directions at various times, revealing a key role for Late Neolithic cultures in shaping modern Central European genetic diversity. Expand
Ancient DNA from South-East Europe Reveals Different Events during Early and Middle Neolithic Influencing the European Genetic Heritage
TLDR
It is proposed that permeation of mtDNA lineages from a second wave of Middle-Late Neolithic migration from North-West Anatolia into the Balkan Peninsula and Central Europe represent an important contribution to the Genetic shift between Early and Late Neolithic populations in Europe, and consequently to the genetic make-up of modern European populations. Expand
Ancient DNA Reveals Prehistoric Gene-Flow from Siberia in the Complex Human Population History of North East Europe
TLDR
Comparing genetic data from ancient and modern-day populations revealed significant changes in the mitochondrial makeup of North East Europeans through time, which suggests an important role of post-Mesolithic migrations from Western Europe and subsequent population replacement/extinctions. Expand
Ancient DNA from an Early Neolithic Iberian population supports a pioneer colonization by first farmers
TLDR
A Bayesian coalescence‐based simulation approach is used to identify the most likely of three demographic scenarios that might explain the genetic data of the Early Neolithic population, and finds that models that ignore population structure are unlikely to explain the data. Expand
Ancient DNA reveals male diffusion through the Neolithic Mediterranean route
TLDR
The Y-haplotype lineages characterized and the study of their current repartition in European populations confirm a greater influence of the Mediterranean than the Central European route in the peopling of southern Europe during the Neolithic transition. Expand
Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans.
TLDR
The results reveal that the current diversity and distribution of haplogroup H were largely established by the Mid Neolithic, but with substantial genetic contributions from subsequent pan-European cultures such as the Bell Beakers expanding out of Iberia in the Late Neolithic (~2800 BC). Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 48 REFERENCES
The Origins and Spread of Agriculture and Pastoralism in Eurasia
Introduction, David Harris. Part 1 Thematic perspectives: growing plants and raising animals - an anthropological perspective on domestication, Tim Ingold ecology, evolutionary theory andExpand
Europe in the Neolithic: The Creation of New Worlds
1. The time of ancestors 2. Keeping the land: indigenous foragers, c.9000-after 7000 BC 3. The first generations: south-east Europe, c.7000/6500-5500 BC 4. Old and new histories: south-east Europe,Expand
Europe's First Farmers
List of illustrations List of tables Preface List of contributors 1. Europe's first farmers: an introduction T. Douglas Price 2. South-eastern Europe in the transition to agriculture in Europe:Expand
The Community Matrix and the Number of Species in a Community
TLDR
The number of species that will be held in stable equilibrium in a community of competing organisms, using the general form of the Lotka-Volterra competition equations for m species, is concerned. Expand
PARADOX OF ENRICHMENT IN COMPETITIVE SYSTEMS
TLDR
Simply testing for the effects of enrich- ment in a controlled situation, where natural competitors may be absent, will not be sufficient to predict the potential results of resource modification in natural systems. Expand
References and Notes
our experimentation could eventually be used to discredit our findings, should they happen not to agree with the original observations. It seems important that all experiments in the rapidlyExpand
疟原虫var基因转换速率变化导致抗原变异[英]/Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A
抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。
  • 2005
Proc. Biol. Sci
  • Proc. Biol. Sci
  • 2005
unpublished data (Estonian
  • Biocentre Database
  • 2005
...
1
2
3
4
5
...