Ancestral and novel roles of Pax family genes in mollusks

  title={Ancestral and novel roles of Pax family genes in mollusks},
  author={Maik Scherholz and Emanuel Redl and Tim Wollesen and Andr{\'e} L. M. de Oliveira and Christiane Todt and Andreas Wanninger},
  booktitle={BMC Evolutionary Biology},
Pax genes are transcription factors with significant roles in cell fate specification and tissue differentiation during animal ontogeny. Most information on their tempo-spatial mode of expression is available from well-studied model organisms where the Pax-subfamilies Pax2/5/8, Pax6, and Paxα/β are mainly involved in the development of the central nervous system (CNS), the eyes, and other sensory organs. In certain taxa, Pax2/5/8 seems to be additionally involved in the development of excretion… CONTINUE READING
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