Anatomy of the Coiled Coil and Its Role in the Conformational Change of Influenza Hemagglutinin

Abstract

The identification of an unexpected coiled-coil sequence in influenza hemagglutinin (HA) led to a model for the conformational change required for the membrane-fusion function of this protein (Chapter 2). Analysis of coiled-coil peptides corresponding to the fusion-active conformation of HA not only support the model, but led to a prediction for the… (More)

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@inproceedings{CarrAnatomyOT, title={Anatomy of the Coiled Coil and Its Role in the Conformational Change of Influenza Hemagglutinin}, author={Marguerite Carr and Peter S. Kim and Frank Solomon and Lawrence Silas Carr and Dwight Herrick Macduff and Josephine M Y Cheung} }