Anatomy and physiology predict response to motor cortex stimulation after stroke.

@article{Nouri2011AnatomyAP,
  title={Anatomy and physiology predict response to motor cortex stimulation after stroke.},
  author={Sarvenaz Nouri and Steven C. Cramer},
  journal={Neurology},
  year={2011},
  volume={77 11},
  pages={1076-83}
}
OBJECTIVES Preclinical studies found that epidural motor cortex stimulation improved motor deficits after stroke, but a phase III trial in humans did not corroborate these results. The current retrospective analysis examined subjects randomized to stimulation in order to identify features distinguishing responders from nonresponders. METHODS Anatomic (MRI measures of gray matter thickness and of white matter tract injury) and physiologic methods (motor evoked responses) were examined as… CONTINUE READING
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