Anatomy and development of the human taste system.

@article{Witt2019AnatomyAD,
  title={Anatomy and development of the human taste system.},
  author={Martin Witt},
  journal={Handbook of clinical neurology},
  year={2019},
  volume={164},
  pages={
          147-171
        }
}
  • M. Witt
  • Published 2019
  • Biology
  • Handbook of clinical neurology
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References

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Mucosa and taste buds of the human epiglottis
TLDR
The position of taste buds around the human mouth, pharynx and larynx is outlined in many texts but it is surprising that literature on their distribution on the human epiglottis is not available.
Innervation of developing human taste buds. An immunohistochemical study
TLDR
Autonomic and somatosensory nerves seem not to play a key role in formation and maintenance of early human taste buds for developmental stages of 7–18 postovulatory weeks.
Neurobiology of the gustatory-salivary reflex.
TLDR
The nucleus of the solitary tract (NST) in the brainstem plays a pivotal role in the neural processing of chemosensory information derived from stimulation of taste buds.
Progress and renewal in gustation: new insights into taste bud development
TLDR
How taste buds are established during development is discussed, highlighting the cellular and molecular mechanisms governing taste cell formation and turnover and how these findings aid the understanding of how and why many cancer therapies result in taste dysfunction.
THE COURSE OF THE NERVE FIBERS TRANSMITTING SENSATION OF TASTE
In 1822, Francois Magendie after dividing the trigeminal nerve within the skull in dogs made the following statement: "The question of taste, formerly so obscure, no longer presents any difficulty.
Nutrient tasting and signaling mechanisms in the gut. IV. There is more to taste than meets the tongue.
TLDR
The thesis is that gustation should be thought of as an integral part of a distributed, interacting multimodal system in which information from other systems, including the GI system, can modulate the taste of food.
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TLDR
The valuable researches of Drasch' and Hermann on the more intimate structure of the gustatory papillae and taste-bulbs throw light upon several important questions which had hitherto been veiled in almost complete obscurity, but they also reveal new fields of inquiry for the conscientious investigator.
The effects of beta-bungarotoxin on the morphogenesis of taste papillae and taste buds in the mouse.
TLDR
Results implicate a significant role for innervation in taste papillae and taste bud morphogenesis in the mouse and suggest that sensory innervation is essential for maintenance of taste buds.
Immunohistochemical distribution of CD44 and some of its isoforms during human taste bud development
TLDR
It is presumed that CD44 is involved in local binding, reuptake, and degradation of hyaluronan in the early stages of taste bud formation, and likely that marginal cells are of the utmost importance for the development and maturation of taste buds.
Differential Expression of α-Gustducin in Taste Bud Populations of the Rat and Hamster
TLDR
The hypothesis that α-gustducin is involved in the transduction of both sweet- and bitter-tasting stimuli by mammalian taste receptor cells is supported.
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