Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions.

@article{Sesack2003AnatomicalSF,
  title={Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions.},
  author={Susan R. Sesack and David B. Carr and Natalia Omelchenko and Aline Silva de Paula Pinto},
  journal={Annals of the New York Academy of Sciences},
  year={2003},
  volume={1003},
  pages={36-52}
}
For normal regulation of motor, affective, and cognitive functions, dopamine provides an essential modulation of glutamate transmission within multiple brain regions. This paper will review three principal anatomical substrates for such interactions. First, dopamine modulates the activity of glutamate neurons within the cerebral cortex. Evidence will be reviewed for dopamine regulation of pyramidal neurons in the prefrontal cortex via synaptic and extrasynaptic mechanisms and through indirect… CONTINUE READING
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Such convergence will be reviewed for the basal ganglia , prefrontal cortex , and amygdala .
Such convergence will be reviewed for the basal ganglia , prefrontal cortex , and amygdala .
Such convergence will be reviewed for the basal ganglia , prefrontal cortex , and amygdala .
Such convergence will be reviewed for the basal ganglia , prefrontal cortex , and amygdala .
Such convergence will be reviewed for the basal ganglia , prefrontal cortex , and amygdala .
Such convergence will be reviewed for the basal ganglia , prefrontal cortex , and amygdala .
Such convergence will be reviewed for the basal ganglia , prefrontal cortex , and amygdala .
Evidence will be reviewed for dopamine regulation of pyramidal neurons in the prefrontal cortex via synaptic and extrasynaptic mechanisms and through indirect effects mediated by GABA cells .
Evidence will be reviewed for dopamine regulation of pyramidal neurons in the prefrontal cortex via synaptic and extrasynaptic mechanisms and through indirect effects mediated by GABA cells .
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