Anatomical effects of dexamethasone intravitreal implant in diabetic macular oedema: a pooled analysis of 3-year phase III trials

@inproceedings{Danis2016AnatomicalEO,
  title={Anatomical effects of dexamethasone intravitreal implant in diabetic macular oedema: a pooled analysis of 3-year phase III trials},
  author={Ronald P. Danis and Srinivas R. Sadda and Xiao-yan Li and Harry Cui and Yehia Hashad and Scott M. Whitcup},
  booktitle={The British journal of ophthalmology},
  year={2016}
}
BACKGROUND/AIM To assess long-term effects of dexamethasone intravitreal implant (DEX implant) monotherapy on retinal morphology in diabetic macular oedema (DME). METHODS Two multicentre, masked, phase III studies with identical protocols randomised patients with DME, best-corrected visual acuity of 34-68 Early Treatment Diabetic Retinopathy Study letters and central subfield retinal thickness (CSRT) ≥300 µm to DEX implant 0.7, 0.35 mg or sham procedure. Patients were followed up for 3 years… CONTINUE READING
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