Anatomical and physiological plasticity of dendritic spines.

@article{Alvarez2007AnatomicalAP,
  title={Anatomical and physiological plasticity of dendritic spines.},
  author={Veronica A. Alvarez and Bernardo L. Sabatini},
  journal={Annual review of neuroscience},
  year={2007},
  volume={30},
  pages={
          79-97
        }
}
In excitatory neurons, most glutamatergic synapses are made on the heads of dendritic spines, each of which houses the postsynaptic terminal of a single glutamatergic synapse. We review recent studies demonstrating in vivo that spines are motile and plastic structures whose morphology and lifespan are influenced, even in adult animals, by changes in sensory input. However, most spines that appear in adult animals are transient, and the addition of stable spines and synapses is rare. In vitro… 

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