Anastomotic complications after Ivor Lewis esophagectomy in patients treated with neoadjuvant chemoradiation are related to radiation dose to the gastric fundus.

@article{Walle2012AnastomoticCA,
  title={Anastomotic complications after Ivor Lewis esophagectomy in patients treated with neoadjuvant chemoradiation are related to radiation dose to the gastric fundus.},
  author={Caroline Vande Walle and Wim P Ceelen and Tom Boterberg and D. Vande Putte and Yves van Nieuwenhove and Oswald Varin and Piet Pattyn},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={82 3},
  pages={e513-9}
}
PURPOSE Neoadjuvant chemoradiation (CRT) is increasingly used in locally advanced esophageal cancer. Some studies have suggested that CRT results in increased surgical morbidity. We assessed the influence of CRT on anastomotic complications in a cohort of patients who underwent CRT followed by Ivor Lewis esophagectomy. PATIENTS AND METHODS Clinical and pathologic data were collected from all patients treated with neoadjuvant CRT (36 Gy combined with 5-fluorouracil and cisplatin) followed by… CONTINUE READING
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