Anastatins A and B, new skeletal flavonoids with hepatoprotective activities from the desert plant Anastatica hierochuntica.

@article{Yoshikawa2003AnastatinsAA,
  title={Anastatins A and B, new skeletal flavonoids with hepatoprotective activities from the desert plant Anastatica hierochuntica.},
  author={Masayuki Yoshikawa and Fengming Xu and Toshio Morikawa and Kiyofumi Ninomiya and Hisashi Matsuda},
  journal={Bioorganic & medicinal chemistry letters},
  year={2003},
  volume={13 6},
  pages={1045-9}
}
New skeletal flavonoids, anastatins A and B, were isolated from the methanolic extract of an Egyptian medicinal herb, the whole plants of Anastatica hierochuntica. Their flavanone structures having a benzofuran moiety were determined on the basis of chemical and physicochemical evidence. Anastatins A and B were found to show hepatoprotective effects on D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes and their activities were stronger than those of related flavonoids… CONTINUE READING

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