Anaplastic thyroid carcinoma: three protocols combining doxorubicin, hyperfractionated radiotherapy and surgery

@article{Tennvall2002AnaplasticTC,
  title={Anaplastic thyroid carcinoma: three protocols combining doxorubicin, hyperfractionated radiotherapy and surgery},
  author={Jan G Tennvall and G{\"o}ran Lundell and Peter Wahlberg and Anders Bergenfelz and Lars Grimelius and M. A. Akerman and A-L Hjelm Skog and G{\"o}ran S. Wallin},
  journal={British Journal of Cancer},
  year={2002},
  volume={86},
  pages={1848 - 1853}
}
Patients with anaplastic thyroid carcinoma can rarely be cured, but every effort should be made to prevent death due to suffocation. Between 1984 and 1999, 55 consecutive patients with anaplastic thyroid carcinoma were prospectively treated according to a combined regimen consisting of hyperfractionated radiotherapy, doxorubicin, and when feasible surgery. Radiotherapy was carried out for 5 days a week. The daily fraction until 1988 was 1.0 Gy × 2 (A) and 1989–92 1.3 Gy × 2 (B) . Thereafter 1.6… CONTINUE READING