Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies.

@article{Smallridge2008AnaplasticTC,
  title={Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies.},
  author={Robert Christian Smallridge and Laura Ann Marlow and John Alton Copland},
  journal={Endocrine-related cancer},
  year={2008},
  volume={16 1},
  pages={
          17-44
        }
}
Anaplastic thyroid cancer (ATC) is a rare malignancy. While external beam radiation therapy has improved locoregional control, the median survival of approximately 4 months has not changed in more than half a century due to uncontrolled systemic metastases. The objective of this study was to review the literature in order to identify potential new strategies for treating this highly lethal cancer. PubMed searches were the principal source of articles reviewed. The molecular pathogenesis of ATC… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 220 REFERENCES

Future in vivo studies would benefit from an orthotopic model, which recreates the clinical presentation of local neck invasion and distant metastases

docetaxel Meng
  • (Kim et al. 2005a,b)
  • 2008
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Inhibition of DJ-1 by siRNA, or overexpression of DJ-1, can sensitize or make cells less sensitive to TRAIL-induced apoptosis

induced apoptosis
  • (Zhang et al
  • 2008
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Genome-wide appraisal of thyroid cancer progression.

  • The American journal of pathology
  • 2002
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Of 55 patients treated over 15 years, 40 had surgery initially. While local control occurred in 60%, median, and 1 year survival

Tennvall
  • 2002
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Cell cycle Cell cycle

Antonelli
  • 2008
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

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