Anaplastic lymphoma of the cervical esophagus presenting as a tracheoesophageal fistula

@article{Joshi2008AnaplasticLO,
  title={Anaplastic lymphoma of the cervical esophagus presenting as a tracheoesophageal fistula},
  author={Anil Joshi and Paul A. Fields and Ricard Sim{\'o}},
  journal={Head \& Neck},
  year={2008},
  volume={30}
}
Anaplastic kinase‐1 positive lymphoma (ALK‐1) is a very rare but distinct pathologic entity. ALK‐1 lymphoma tends to affect the bone marrow, skin, lungs, soft tissue, but very rarely the gastrointestinal tract. 
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11 Citations

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Citation Type

High-Dose Chemotherapy With Autologous Stem Cell Transplantation in a Case of Refractory Peripheral T Cell Lymphoma With Tracheoesophageal Fistula: A Case Report
Primary Gastrointestinal T-Cell Lymphoma and Indolent Lymphoproliferative Disorders: Practical Diagnostic and Treatment Approaches
TLDR
This review provides a cross-sectional comparison of histological findings and summarized up-to-date clinically relevant information including the treatment strategies as well as practical differential diagnosis based on thorough literature review of primary gastrointestinal T-cell neoplasms.
Successful treatment of post chemotherapy esophageal cicatricial atresia in a pediatric patient with anaplastic large cell lymphoma through minimally invasive esophagectomy: a case report
TLDR
Oncologists must consider the possibility of acquired esophageal cicatricial atresia as a complication during chemotherapy for ALCL as well as useful treatment options for maintaining oral intake in an 11-year-old boy who complained of abdominal pain and cough.
ALK-positive anaplastic large cell lymphoma presenting multiple lymphomatous polyposis: A case report and literature review
TLDR
The macroscopic/endoscopic features of gastrointestinal ALK+ ALCL may be more similar to those of B-cells lymphomas rather than T-cell lymphomas, and the endoscopic features in this case were thought to be similar toThose of MCL.
PAX-5 positive anaplastic large cell lymphoma presenting by dysphagia; a case report
TLDR
This case illustrated an unusual presentation of primary Non Hodgkin lymphoma of Esophagus of esophagus in a 16-year-old boy who initially presented with dysphagia.
Primary esophageal diffuse large B cell lymphoma presenting with tracheoesophageal fistula: A rare case and review
TLDR
A rare incident of a primary diffuse large B-cell lymphoma presented as tracheoesophageal fistula in a patient with cough, dysphagia and weight loss is detailed.
Primary gastrointestinal anaplastic large cell lymphoma.
Spectrum of CT Findings in Thoracic Extranodal Non-Hodgkin Lymphoma.
TLDR
A comprehensive review illustrates the spectrum of CT manifestations of extranodal NHL in the chest, including the pleura, lung, airways, heart, pericardium, esophagus, chest wall, and breast.
Anaplastic Large-Cell Lymphoma Presenting as a Nasopharyngeal Mass and Cervical Lymphadenopathy
TLDR
The second reported case of anaplastic lymphoma kinase-positive anaplastics large-cell lymphoma presenting in an adult with an obstructing adenoid/nasopharyngeal mass and lymphadenopathy is presented.
Chapter 5 – Lymphomas of the Esophagus, Gastrointestinal Tract, Hepatobiliary Tract, and Pancreas
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References

SHOWING 1-10 OF 12 REFERENCES
Peripheral T-cell Lymphomas: Clinical Features and Prognostic Factors of 92 Cases Defined by the Revised European American Lymphoma Classification
TLDR
The International Prognostic Index (IPI) was a significant prognostic factor for both progression-free and OS in patients with PTCL and ALK expression may not provide prognostic information for systemic ALCL.
Histology Impacts the Outcome of Peripheral T-Cell Lymphomas after High Dose Chemotherapy and Stem Cell Transplant
TLDR
ALCL histology confers better survival compared to non-ALCL and DLBCL histologies, and ALK-positive ALCL is associated with the best EFS after relapse with HDC and SCT.
Survivin expression predicts poorer prognosis in anaplastic large-cell lymphoma.
TLDR
Survivin is expressed in approximately half of ALCL tumors and independently predicts unfavorable clinical outcome, and modulation of survivin expression or function may provide a novel target for experimental therapy in patients with ALCL.
Prognostic significance of CD56 expression for ALK-positive and ALK-negative anaplastic large-cell lymphoma of T/null cell phenotype.
TLDR
It is suggested that effective therapeutic approaches should be explored for high-risk ALCL patients, who can be identified by means of a prognostic model, including CD56, which is not a marker to identify a distinct subtype of ALCL, but a strong clinical prognostic factor.
Lymphoma : Clinico-Pathological Findings and Outcome
TLDR
Multivariate analysis identified ALK expression and the International Prognostic Index as independent variables that were able to predict survival among T/null primary, systemic anaplastic large-cell lymphoma.
ALK expression defines a distinct group of T/null lymphomas ("ALK lymphomas") with a wide morphological spectrum.
A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project.
TLDR
It is found that the ILSG classification can be readily applied and identifies clinically distinctive types of NHL, however, for clinical application, prognostic factors as defined by the International Prognostic Index must be combined with the histologic diagnosis for appropriate clinical decisions.
Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1.
TLDR
Results indicate that reliable immunostaining of routine biopsy material for NPM-ALK and ALK proteins is feasible and of diagnostic importance, especially because t(2;5)+ ALCL cases have a good prognosis with appropriate treatment.
A predictive model for aggressive non-Hodgkin's lymphoma.
TLDR
The international index and the age-adjusted international index should be used in the design of future therapeutic trials in patients with aggressive non-Hodgkin's lymphoma and in the selection of appropriate therapeutic approaches for individual patients.
The International Non - Hodgkin ’ s Lymphoma Prognostic Factors Project : a predictive model for aggressive non - Hodgkin ’ s lymphoma
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