Anaplastic lymphoma kinase-positive large B-cell lymphoma with complex karyotype and novel ALK gene rearrangements.

@article{Shi2011AnaplasticLK,
  title={Anaplastic lymphoma kinase-positive large B-cell lymphoma with complex karyotype and novel ALK gene rearrangements.},
  author={Min Shi and Patricia Minehart Miron and Lloyd Hutchinson and Bruce A. Woda and Rajneesh Nath and J{\'a}n Cern{\'y} and Hongbo Yu},
  journal={Human pathology},
  year={2011},
  volume={42 10},
  pages={1562-7}
}
Anaplastic lymphoma kinase-positive large B-cell lymphoma is a rare non-Hodgkin lymphoma that exhibits a characteristic immunoblastic/plasmablastic morphology and is frequently associated with t(2;17)(p23;q23) and expression of Clathrin-anaplastic lymphoma kinase fusion protein. Here, we report a refractory anaplastic lymphoma kinase-positive large B-cell lymphoma in a 49-year-old human immunodeficiency virus-positive man. The neoplastic cells expressed CD138, epithelial membrane antigen, CD45… CONTINUE READING
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