Anaplastic large cell lymphoma: another entity in the differential diagnosis of small round blue cell tumors.

@article{Gustafson2009AnaplasticLC,
  title={Anaplastic large cell lymphoma: another entity in the differential diagnosis of small round blue cell tumors.},
  author={Steven A Gustafson and L Jeffrey Medeiros and Neda Kalhor and Carlos E Bueso-Ramos},
  journal={Annals of diagnostic pathology},
  year={2009},
  volume={13 6},
  pages={413-27}
}
We saw in consultation a biopsy specimen from a 6-year old girl with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL). The tumor arose in soft tissue of the neck, and diagnostic tissue was obtained by core needle biopsy. Histologically, the neoplasm was cellular without pattern. Immunohistochemical workup with a large panel of antibodies at another institution showed immunoreactivity for NB84 and neuron specific enolase (dim). Antibodies specific for CD3, CD20… CONTINUE READING
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