Anaphase DNA bridges induced by lack of RecQ5 in Drosophila syncytial embryos.

Abstract

Drosophila melanogaster RecQ5, a member of the RecQ family, is expressed in early embryos. The loss of maternally-derived RecQ5 leads to spontaneous mitotic defects in syncytial embryos. We demonstrate that the mitotic defects are derived from anaphase DNA bridges. Pairs of daughter nuclei that had been linked by the bridges concurrently exited from the… (More)
DOI: 10.1016/j.febslet.2011.04.074

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